Experimental study of an evanescent-field biosensor based on 1D photonic bandgap structures

• Jad Sabek,
• Francisco Javier Díaz-Fernández,
• Luis Torrijos-Morán,
• Zeneida Díaz-Betancor,
• Ángel Maquieira,
• María-José Bañuls,
• Elena Pinilla-Cienfuegos and
• Jaime García-Rupérez

Beilstein J. Nanotechnol. 2019, 10, 967–974, doi:10.3762/bjnano.10.97

• sites towards the target sample. Then, the biofunctionalized PBG biosensor has been used to perform a direct and real-time detection of the target BSA antigen. Keywords: evanescent field; half-antibodies; light-assisted immobilization; photonic bandgap sensor; SNOM characterization; Introduction The

• demonstrated in [9][10], where the light-assisted immobilization of the half-antibodies was monitored in real time and in-flow using PBG sensing structures; however, a low sensing response towards antigen detection was obtained when using that in-flow biofunctionalization implementation. Therefore, in this

• distance between the sensor surface and the recognition sites, and provides a proper orientation of these recognition sites. This biofunctionalization process, as well as the protocol for obtaining the half-antibodies, was previously described in [9][10], where the light-assisted immobilization of the half